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Ki Whan Hong Selected Research

Cilostazol (Pletal)

1/2020Retraction: Inhibition of HMGB1-Induced Angiogenesis by Cilostazol via SIRT1 Activation in Synovial Fibroblasts from Rheumatoid Arthritis.
12/2019Cilostazol add-on therapy for celecoxib synergistically inhibits proinflammatory cytokines by activating IL-10 and SOCS3 in the synovial fibroblasts of patients with rheumatoid arthritis.
8/2019Multitarget-directed cotreatment with cilostazol and aripiprazole for augmented neuroprotection against oxidative stress-induced toxicity in HT22 mouse hippocampal cells.
8/2019Multitarget-based cotreatment with cilostazol and celecoxib synergistically suppresses collagen-induced arthritis in mice by enhancing interleukin-10 expression.
1/2019Augmented improvement of cognition and memory by aripiprazole add-on for cilostazol treatment in the chronic cerebral hypoperfusion mouse model.
2/2017Antidepressant Effects of Aripiprazole Augmentation for Cilostazol-Treated Mice Exposed to Chronic Mild Stress after Ischemic Stroke.
3/2016Anti-depressant effects of phosphodiesterase 3 inhibitor cilostazol in chronic mild stress-treated mice after ischemic stroke.
10/2015Suppression of RANKL-induced osteoclast differentiation by cilostazol via SIRT1-induced RANK inhibition.
9/2014Probucol plus cilostazol attenuate hypercholesterolemia‑induced exacerbation in ischemic brain injury via anti-inflammatory effects.
2/2014Attenuation of β-amyloid-induced tauopathy via activation of CK2α/SIRT1: targeting for cilostazol.
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Ki Whan Hong Research Topics

Disease

10Infarction (Infarctions)
08/2016 - 03/2002
9Rheumatoid Arthritis
01/2020 - 03/2010
7Ischemia
05/2011 - 03/2002
6Experimental Arthritis
08/2019 - 03/2010
6Atherosclerosis
09/2014 - 03/2004
6Brain Ischemia (Cerebral Ischemia)
09/2014 - 03/2002
6Cerebral Infarction
01/2008 - 03/2002
5Hypotension (Low Blood Pressure)
01/2004 - 05/2002
4Stroke (Strokes)
03/2016 - 01/2006
4Alzheimer Disease (Alzheimer's Disease)
01/2016 - 02/2014
3Ischemic Stroke
02/2017 - 03/2016
3Inflammation (Inflammations)
01/2016 - 08/2010
3Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
09/2014 - 06/2007
3Insulin Resistance
05/2009 - 08/2006
3Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage)
01/2003 - 07/2002
2Vascular Dementia (Subcortical Arteriosclerotic Encephalopathy)
08/2019 - 01/2019
2Hypercholesterolemia
09/2014 - 08/2011
2Arthritis (Polyarthritis)
01/2014 - 11/2013
2Cognitive Dysfunction
05/2011 - 12/2007
2Edema (Dropsy)
01/2008 - 12/2003
2Neuroblastoma
01/2006 - 01/2004
2Glioblastoma (Glioblastoma Multiforme)
08/2004 - 09/2003
1Insulinoma
12/2021
1Psychotic Disorders (Schizoaffective Disorder)
12/2017
1Hyperlipidemias (Hyperlipidemia)
08/2016
1Neuroinflammatory Diseases
08/2016
1Hypoxia (Hypoxemia)
04/2015
1Synovitis
04/2015
1Brain Injuries (Brain Injury)
09/2014
1Tauopathies
02/2014
1Neoplasms (Cancer)
08/2010
1Carcinogenesis
08/2010
1Gastritis
08/2010
1Stomach Neoplasms (Stomach Cancer)
08/2010
1Stomach Ulcer (Gastric Ulcer)
08/2010
1Type 2 Diabetes Mellitus (MODY)
05/2009

Drug/Important Bio-Agent (IBA)

34Cilostazol (Pletal)FDA LinkGeneric
01/2020 - 03/2002
5Sirtuin 1IBA
01/2020 - 01/2014
5Probucol (Lorelco)FDA Link
08/2016 - 07/2007
5Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2006 - 03/2002
4Aripiprazole (Abilify)FDA Link
08/2019 - 02/2017
4Amyloid (Amyloid Fibrils)IBA
01/2016 - 02/2014
4Proteins (Proteins, Gene)FDA Link
04/2015 - 01/2014
4Superoxides (Superoxide)IBA
05/2005 - 07/2002
4NADPH Oxidases (NAD(P)H oxidase)IBA
01/2004 - 07/2002
3CytokinesIBA
12/2019 - 03/2010
3Neuroprotective AgentsIBA
08/2019 - 03/2002
3AntioxidantsIBA
08/2016 - 04/2002
3Peptides (Polypeptides)IBA
01/2016 - 11/2014
3TensinsIBA
08/2004 - 09/2003
2Interleukin-10 (Interleukin 10)IBA
12/2019 - 08/2019
2Celecoxib (Celebrex)FDA Link
12/2019 - 08/2019
2Apolipoproteins E (ApoE)IBA
08/2016 - 08/2011
2LipidsIBA
08/2016 - 09/2014
2CholesterolIBA
08/2016 - 05/2005
2Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA
09/2012 - 05/2009
2Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
08/2011 - 10/2003
2PPAR gammaIBA
05/2009 - 12/2008
2Glucose (Dextrose)FDA LinkGeneric
12/2008 - 09/2007
2Cyclic AMP (AMP, Cyclic)IBA
01/2008 - 03/2002
2Large-Conductance Calcium-Activated Potassium Channels (Maxi-K Channels)IBA
01/2006 - 03/2004
2Vasodilator Agents (Vasodilators)IBA
01/2006 - 05/2002
2iberiotoxinIBA
01/2006 - 03/2004
2N''- cyano- N- (6- amino- 3,4- dihydro- 3- hydroxy- 2- methyl- 2- dimethoxymethyl- 2H- benzopyran- 4- yl)- N'- benzylguanidineIBA
08/2004 - 04/2002
2Superoxide Dismutase-1IBA
01/2004 - 01/2003
2Phosphoric Monoester Hydrolases (Phosphatases)IBA
01/2004 - 09/2003
2Calcitonin Gene-Related PeptideIBA
01/2003 - 05/2002
2Cromakalim (Levcromakalim)IBA
01/2003 - 05/2002
1Insulin (Novolin)FDA Link
12/2021
1DA-1241IBA
12/2021
1InterleukinsIBA
08/2019
1Antidepressive Agents (Antidepressants)IBA
02/2017
1Protein Kinases (Protein Kinase)IBA
01/2017
1Adenosine Monophosphate (AMP)IBA
01/2017
1LDL CholesterolIBA
08/2016
1Brain-Derived Neurotrophic Factor (BDNF)IBA
03/2016
1Phosphodiesterase 3 InhibitorsIBA
03/2016
1HMGB1 Protein (HMG1)IBA
04/2015
1Neutralizing AntibodiesIBA
04/2015
1Nuclear Proteins (Protein, Nuclear)IBA
04/2015
1Amyloid Precursor Protein Secretases (beta-Secretase)IBA
11/2014
1Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA
09/2014
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2014
1rho-Associated KinasesIBA
11/2013
1Interleukin-23 (Interleukin 23)IBA
11/2013
1Methotrexate (Mexate)FDA LinkGeneric
09/2012
1Phenobarbital (Luminal)FDA Link
08/2011
1AdiponectinIBA
08/2011
1Type 3 Cyclic Nucleotide PhosphodiesterasesIBA
05/2011
1IntegrinsIBA
05/2011
11-dodecylpyridoxal (PLD)IBA
08/2010
1Pharmaceutical PreparationsIBA
08/2010
1Phospholipase DIBA
08/2010
1rebamipideIBA
08/2010
1ChemokinesIBA
08/2010
1Heme Oxygenase-1IBA
03/2010
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
05/2009
1Bromodeoxyuridine (BrdU)IBA
01/2009

Therapy/Procedure

7Therapeutics
12/2019 - 01/2003
1Cell- and Tissue-Based Therapy (Cell Therapy)
05/2011